The International Normalized Ratio (INR) is the recommended method for monitoring warfarin, and the target goal is set by the provider, based on clinical indication. An INR goal of 2 to 3 may be appropriate for treatment or prevention on thromboembolism; higher targets of to may be appropriate for high-risk Baseline INR and CBC should be obtained prior to initiation of warfarin therapy, and reassessed until the therapeutic range has been reached. It can take 2-3 days for the INR to reflect a change in the dosage, so daily increases in the dose to meet the target goal are usually not appropriate. If a patient is transitioning from IV heparin to PO warfarin, heparin should be continued for at least 24 hours after the INR reaches the ordered target range. Daily monitoring of PT/INR and aPTT is recommended for patients concurrently on heparin and warfarin.